Recent business shutdowns and changes to normal routines related to mitigation efforts for the 2019 novel coronavirus disease (COVID-19) have caused daily weekday electricity demand in the central region of the United States to decrease by 9%–13% in March and April compared with expected demand, after accounting for seasonal temperature changes. This decrease is similar to declines seen in New York. In contrast, other areas of the country, such as Florida, have not experienced significant changes, which may partly be caused by regional differences in how much electricity each end-use sector consumes and the varying effects of COVID-19 mitigation efforts on the sectors.